Cytotoxicity assays

Quantification of killer- cell- mediated cytotoxicity is of great importance in onco-immunotherapy. Treated cells or supernatants or any drug candidate could be tested in an in-vitro setting to determine their effect in a cell specific killing activity of CTL. Melanoma cells could be used as a target for TAA-specific T cells in a testing platform using LDH Cytotoxicity for the readout.